Inadequately planned factory layouts can lead to higher operational costs. The planning process is time-consuming and multiple planning parameters must be considered simultaneously, leading to large solution spaces. Automated planning approaches can support the planning team in the early phases of layout planning by generating layout variants that can afterwards be further specified. Recent studies from other disciplines have shown the potential of Quantum Annealing (QA) to solve complex assignment problems within seconds. Consequently, this paper presents a first implementation of a QA-based layout planning approach and demonstrates its advantages regarding scalability, solution quality, and computing time.